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Epic Code LAB1231022 Meningitis/Encephalitis Panel PCR

Important Note

Due to challenging result interpretation, it is recommended to discuss with Infectious Disease prior to ordering this test.

Test Name Alias

FilmArray ME panel |  MENINGITIS/ENCEPHALITIS PANEL PCR (INFECTIOUS DISEASE ONLY)

Interface Order Alias

1231022

Clinical Information

This PCR panel is used to detect the following pathogens from cerebrospinal fluid: Escherichia coli K1, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, Cytomegalovirus (CMV), Enterovirus, Herpes simplex virus 1 (HSV-1), Herpes simplex virus 2 (HSV-2), Human herpes virus 6 (HHV-6), Human parechovirus, Varicella zoster virus (VZV), and Cryptococcus neoformans/gattii. 

Due to reduced sensitivity, testing of spinal fluid for HSV-1/HSV-2 by another molecular method or for cryptococcal antigen is recommended when these targets are not detected yet clinical suspicion is high.

Collection Instructions

Specimen Collection: Cerebrospinal fluid (CSF)

 

Container(s): CSF Tube

Preferred Volume to Collect: 1.0 mL

Minimum Volume to Collect: 0.5 mL

Neonate Volume to Collect: 0.5 mL

Collection Instructions:

  • IMPORTANT: Label container with:
    • Number containers/tube in order of collection
    • Patient information
    • Specimen source
    • Date of collection
  • Specimen must be received within one hour of collection.
  • Hand deliver to laboratory, do not send through pneumatic tube system
  • This testing should only be collected in an inpatient setting

 

Lab Testing is performed using the following tube designation, regardless of label on tube:

  • Tube 1 = Chemistry 
  • Tube 2 = Microbiology
  • Tube 3 = Hematology
  • Tube 4 = Extra

Transport Temperature: Ambient

Rejection Criteria

  • Frozen specimens

Specimen Stability

Ambient: 24 hours
Refrigerated (4°C):  7 days

Test Frequency

Available daily, usual turn-around time 24 hours

Reference Range

Not detected for all targets

 Please see Critical Values Table

Performing Department

Microbiology/Virology

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

PCR

CPT

87483

CDM Code

3068748301

Epic Test ID

1230102666

LOINC

82180-1

Reviewed Date

9/7/2023