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Epic Code LAB3624 IgE Walnut Component Add-On

Test Name Alias

allergen | ImmunoCAP | Allergen Specific IgE | RAST | Allergy | Tree Nut | 7123

Interface Order Alias

55080

Clinical Information

IgE antibodies to rJug r 1 (Walnut Storage Protein) are associated with systemic reactions to walnuts.

IgE antibodies to rJug r 3 (Walnut LTP) are associated with local as well as systemic reactions to walnuts.

Component testing for Walnut must be ordered as follow-up to whole allergen results. They are not available as reflex tests. Patient specimens are stored frozen for 30 days.

Component testing measures IgE antibodies to individual proteins unlike whole allergen testing which measures the presence of specific immunoglobulin E (sIgE) antibodies to a combination of allergenic and non-allergenic proteins.This next generation testing identifies the source of sensitization and helps the clinician assess the risk of systemic reaction.

Results of component testing can assist with patient selection for oral food challenge as well as possible management recommendations such as immunotherapy and/or allergen avoidance/food elimination. Because of the diagnostic and management complexities associated with food allergy, referral to an allergy and immunology specialist should be considered when evaluating a patient with suspected food allergies.

Specimen Requirements

Specimen Collection: Blood

Container(s): Gold Top (Serum Separator-SST Gel)

Preferred Volume to Collect: 3.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok? Y

Microtainer acceptable? Y

 

Processed specimen: Serum

Centrifuge/Spin: Y

Aliquot: N

Processing instructions: Allow specimen to clot for 30 minutes and centrifuge within 2 hours.

Specimen Transport Temperature

Refrigerate

Rejection Criteria

Quantity not sufficient (QNS)

Specimen Stability

Serum

Ambient: 12 hours

Refrigerate: 7 days

Frozen: aliquot for longer storage

Laboratory Retention: 30 days

Test Frequency

Available Monday through Friday, usual TAT 1-3 days.

Reference Range

<0.35 kU/L

Performing Department

Immunochemistry

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

ImmunoCAP® System Fluorescence Enzyme Immunoassay (FEIA)

CPT

86008, 86008

CDM Code

3028600801

Epic Test ID

1230101920

Mayo Access Code

SHO55080

Reviewed Date

3/4/2024

Updated Date

3/17/2024 – Reference Range (OEE)