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Epic Code LAB1230390 Immature Platelet Fraction (Reflex Only) (Lab Staff Order)

Test Name Alias

Reticulated platelets | immature platelets | young platelets | IPF

Interface Order Alias

1230390

Clinical Information

The immature platelet fraction (IPF) measures the reticulated platelets (platelets containing mRNA) in peripheral blood. IPF reflects the bone marrow thrombopoietic activity, increasing when platelet production rises and decreasing when production falls. Thus, IPF is useful in determining whether the thrombocytopenia is secondary to decreased production (aplastic causes) or peripheral platelet destruction (such as ITP or TTP). IPF is a good predictor of platelet recovery and can be used to monitor the patients rebounding from hematopoietic progenitor cell (HPC) transplantation or chemotherapy.

 

Reference: Kickler TS, Oguni S, Borowitz MJ. Clinical evaluation of high fluorescent platelet fraction percentage in thrombocytopenia. Am J Clin Pathology 2006;125:282-287.

Ordering Instructions

This test cannot be ordered separately, it is only available as a reflex test.

Collection Instructions

Specimen Collection: Blood

 

Container(s): Lavender top (EDTA)

Preferred Volume to Collect: 3.0 mL

Minimum Volume to Collect: 0.5 mL

Neonate Volume to Collect: 0.5 mL

Capillary collect ok? Yes

Microtainer acceptable: Yes

 

Collection Instructions:

  • Gently invert EDTA tube(s) 8 - 10 times immediately after collection.

 

Processing Instructions (Laboratory, Outpatient or Off-site collection)

  • Processed Specimen: Whole Blood EDTA
  • Centrifuge/Spin: No
  • Aliquot: No
  • Transport Temperature: Room Temperature

Rejection Criteria

  • Frozen Specimens
  • Clotted Specimens
  • Specimens with platelet clumps/clumped platelets

Specimen Stability

Ambient: 24 hours

Refrigerated: 48 hours

Frozen: Not acceptable

Laboratory Retention: 72 hours

Reflex Information

Link: MEC approved reflex

Note: Platelet citrate will not reflex

Test Frequency

Available daily, usual TAT 1 day.

Reference Range

Immature Platelet Fraction (IPF %)

0.9 - 8.5%

Immature Platelet Fraction (IPF) Absolute

3.4 - 18.4 x 109/L

 

Performing Department

Hematology

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Corewell Health Big Rapids Laboratory, Big Rapids, MI

Corewell Health Blodgett Laboratory, Grand Rapids, MI

Corewell Health Gerber Laboratory, Fremont, MI

Corewell Health Kelsey Laboratory, Lakeview, MI

Corewell Health Ludington Laboratory, Ludington, MI

Corewell Health Pennock Laboratory, Hastings, MI

Corewell Health Reed City Laboratory, Reed City, MI

Corewell Health Greenville Laboratory, Greenville, MI

Corewell Health Zeeland Laboratory, Zeeland, MI

Methodology

Sysmex XN

CPT

85055

CDM Code

3058505501

Epic Test ID

1230101971

LOINC

Not available

Mayo Access Code

SHO1230390

Reviewed Date

3/17/2023