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Test Code LAB1230390 Immature Platelet Fraction (Reflex Only, Lab Only Orderable)

Test Name Alias

Reticulated platelets | immature platelets | young platelets | IPF

Clinical Information

The immature platelet fraction (IPF) measures the reticulated platelets (platelets containing mRNA) in peripheral blood. IPF reflects the bone marrow thrombopoietic activity, increasing when platelet production rises and decreasing when production falls. Thus, IPF is useful in determining whether the thrombocytopenia is secondary to decreased production (aplastic causes) or peripheral platelet destruction (such as ITP or TTP). IPF is a good predictor of platelet recovery and can be used to monitor the patients rebounding from hematopoietic progenitor cell (HPC) transplantation or chemotherapy.


Reference: Kickler TS, Oguni S, Borowitz MJ. Clinical evaluation of high fluorescent platelet fraction percentage in thrombocytopenia. Am J Clin Pathology 2006;125:282-287.

Ordering Instructions

This test cannot be ordered separately, it is only available as a reflex test.

Collection Instructions

Specimen Collection: Blood


Container(s): Lavender top (EDTA)

Preferred Volume to Collect: 3.0 mL

Minimum Volume to Collect: 0.5 mL

Neonate Volume to Collect: 0.5 mL

Capillary collect ok? Yes

Microtainer acceptable: Yes


Collection Instructions:

  • Gently invert EDTA tube(s) 8 - 10 times immediately after collection.


Processing Instructions (Laboratory, Outpatient or Off-site collection)

  • Processed Specimen: Whole Blood EDTA
  • Centrifuge/Spin: No
  • Aliquot: No
  • Transport Temperature: Room Temperature

Rejection Criteria

  • Frozen Specimens
  • Clotted Specimens
  • Specimens with platelet clumps/clumped platelets

Specimen Stability

Ambient: 24 hours

Refrigerated: 48 hours

Frozen: Not acceptable

Laboratory Retention: 72 hours

Reflex Information

Link: MEC approved reflex

Note: Platelet citrate will not reflex

Test Frequency

Available daily, usual TAT 1 day.

Reference Range

Immature Platelet Fraction (IPF %)

0.9 - 8.5%

Immature Platelet Fraction (IPF) Absolute

3.4 - 18.4 x10^3/uL


Performing Department


Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI

Spectrum Health Big Rapids Laboratory, Big Rapids, MI

Spectrum Health Blodgett Laboratory, Grand Rapids, MI

Spectrum Health Gerber Laboratory, Fremont, MI

Spectrum Health Kelsey Laboratory, Lakeview, MI

Spectrum Health Ludington Laboratory, Ludington, MI

Spectrum Health Pennock Laboratory, Hastings, MI

Spectrum Health Reed City Laboratory, Reed City, MI

Spectrum Health United Laboratory, Greenville, MI

Spectrum Health Zeeland Laboratory, Zeeland, MI


Sysmex XN



CDM Code

Update in Process

Epic Test ID


Interface Order Alias



Not available

Mayo Access Code


Reviewed Date