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Test Code LAB1230554 Beta 2 Glycoprotein, IgG and IgM Antibodies

Test Name Alias

APLS IgG | APLS IgM | B2GPI | Antiphospholipid Antibody | Lupus Anticoagulant Testing Panel

Clinical Information

Cardiolipin IgG/IgM and Beta Glycoprotein 1 IgG/IgM Antibodies when used in conjunction with other clinical findings, aid in the diagnosis of primary Antiphospholipid Syndrome (APS) and those secondary to systemic lupus erythematosus (SLE) or SLE-like disorders. Antibody profiles are encouraged to identify thrombotic risk and may be more useful than individual tests in identifying a patient's risk.

Panel Information

This test is part of Panel: Antiphospholipid Antibody Syndrome Panel [LAB1230572] 

Icons & Photos

Action Icons (time constraints, hand deliver, protect from light or temperatures) or photos of collection devices

Collection Instructions

Specimen Collection: Blood


Container(s): Gold Top (SST Gel)

Preferred Volume to Collect: 5.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok? Yes

Microtainer acceptable: Yes


Collection Instructions:

  • After collection, gently invert tube 8-10 times.
  • Specimen should be processed within 2 hours – See Processing Instructions.

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Serum

Centrifuge/Spin: Yes

Aliquot: No

Processing Instructions:

  • Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.

Transport Temperature: Refrigerate


Specimen Stability

Ambient: 12 Hours

Refrigerate: 7 days (2-8° C)

Frozen: -20°C for longer storage

Laboratory Retention: 7 days

Test Frequency

Test available Monday - Friday. Turn-around time 1 - 3 days.

Reference Range

Both IgG and IgM:

<20 U/mL Negative

≥ 20 U/mL Positive

Performing Department


Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI


Multiplex Flow Immunoassay


86146 x 2

CDM Code

Not available

Epic Test ID


Interface Order Alias



Not available

Mayo Access Code

Not available

Reviewed Date