Sign in →

Epic Code LAB1230663 MyoMarker 3 Profile

Important Note

Specimen Minimum Volume: 4 mL serum (volume does NOT allow for repeat testing).

Performing Laboratory

Esoterix Endocrinology

Specimen Type

Serum


Specimen Required


Collection Container/Tube: 10 mL Red

Submission Container/Tube: Plastic vial

Specimen Volume: 5 mL

Acceptable: SST

Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube is acceptable. Separate serum from cells within 1 hour of collection and send 5 mL of serum refrigerated in a plastic vial.


Laboratory Test Directory Note:

COLLECTION NOTE: Volumes listed are in serum or plasma, draw approximately 2 1/2 times the requested volume in whole blood.

Specimen Minimum Volume

4 mL (volume does NOT allow for repeat testing)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  60 days
  Ambient  7 days

Reject Due To

Gross hemolysis: Reject
Thawing: Warm OK; Cold OK
Gross lipemia: Reject
Gross icterus Reject
Other: Anything other than serum; bacterial contamination

Reference Values

Anti-PL-7 Ab, Anti-PL-12 Ab, Anti-EJ Ab, Anti-OJ Ab, Anti-SRP Ab, Anti-Mi-2-Ab, Anti-U3 RNP (Fibrillarin), Anti-U2 RNP Ab, Anti-Ku Ab:

Reference Range: Negative

 

Interpretation for:

Anti-Jo-1 Ab, Anti-TIF-1gamma Ab, Anti-MDA-5-Ab (CADM-140), Anti-NXP-2 (P140) Ab, Anti-PM/Scl-100 Ab, Anti-SS-A 52kD Ab IgG, Anti-U1-RNP Ab:

Reference Range: <20

Negative: <20 units

Weak Positive: 20-39 units

Moderate Positive: 40-80 units

Strong Positive: >80 units

Clinical Information

The idiopathic inflammatory myopathies (IIM) are a heterogeneous group of disorders characterized by muscle weakness, resulting from chronic muscle inflammation of unknown cause. Patients with IIM have a variety of autoantibodies with various clinical utilities that fall into two main groups. One group of autoantibodies are found in patients with myositis and are known as Myositis Specific Autoantibodies (MSA). The MSAs are highly specific for patients with polymyositis (PM) dermatomyositis (DM), anti-synthetase syndrome and necrotizing myositis. The second group of autoantibodies are considered Myositis Associated Autoantibodies (MAA). These appear in myositis overlap syndrome and in other connective tissue diseases, which correlate with certain clinical and/or pathophysiological conditions.

Reporting Name

MyoMarker 3 Profile

Method Name

Enzyme-linked immunosorbent assay (ELISA); RIPA Gel Radiography

CPT Code Information

83516 x 9

86235 x 7

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FMYO3 MyoMarker 3 Profile Not Provided

 

Result ID Test Result Name Result LOINC Value
Z5677 Anti-Jo-1 Ab 35333-4
Z5678 Anti-PL-7 Ab 33772-5
Z5679 Anti-PL-12 Ab 33771-7
Z5680 Anti-EJ Ab 45149-2
Z5681 Anti-OJ Ab 45152-6
Z5682 Anti-SRP Ab 33921-8
Z5683 Anti-Mi-2-Ab 18485-3
Z5684 Anti-TIF-1gamma Ab 88739-8
Z5685 Anti-MDA-5 Ab (CADM-140) 88725-7
Z5686 Anti-NXP-2 (P140) Ab 82425-0
Z5687 Anti-PM/Scl-100 Ab 31562-2
Z5691 Anti-Ku Ab 18484-6
Z5692 Anti-SS-A 52kD Ab, IgG 70257-1
Z5690 Anti-U1 RNP Ab 57662-9
Z5689 Anti-U2 RNP Ab 68549-5
Z5688 Anti-U3 RNP (Fibrillarin) 49963-2

Report Available

16-25 days

Test Classification

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.