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Epic Code LAB1230753 IgE Cedar

Test Name Alias

allergen | ImmunoCAP | Calocedrus decurrens | RAST | Allergy | Libocedrus decurrens | Allergen Specific IgE

Interface Order Alias

1230753

Clinical Information

All allergens are reported down to a cutoff level of 0.10 kU/L. The significance of allergen specific IgE levels between 0.10 and 0.35 kU/L remains undefined. Cumulative levels of multiple allergen specific IgE antibodies may have an additive effect in producing clinical symptoms.

Individual allergen specific IgE antibody levels may not always correlate with severity of clinical symptoms. Results must be interpreted in the context of the clinical history and the patient’s symptom presentation. Quantitative IgE levels can serve to guide overall disease management by targeted trigger exposure reduction to identified allergens.

 Allergens with a high risk of anaphylaxis (egg, milk, soy, wheat, nuts, seafood, kiwi fruit, latex, insect venoms, drugs) are reported with a reference range of <0.10 kU/L, lower than the <0.35 kU/L reference range used for other routine allergens. IgE antibody levels to these allergens less than 0.10 kU/L do not exclude the possibility of an anaphylactic reaction to the allergen involved, since in vitro assays are indicators of previous sensitization rather than predictors of future response. IgE antibody levels must be interpreted in the context of the clinical history of the patient and the reaction history involved.

Collection Instructions

Specimen Collection: Blood

Container(s): Gold Top (Serum Separator-SST Gel)

Preferred Volume to Collect: Full tube (5 mL)

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok? Yes

Microtainer acceptable: Yes

Collection Instructions:

  • Gently invert gold tube(s) 8 – 10 times to mix clot activator with blood.
  • Specimen should be processed within 2 hours – See Processing Instructions.
  • 1 full tube per 15 – 20 allergens.

 

Processing Instructions (Laboratory, Outpatient or Off-site collection)

  • Processed Specimen: Serum

  • Centrifuge/Spin: Yes

  • Aliquot: No

  • Processing Instructions: 

    • Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours. 

    • Minimum volume: 0.3 mL SERUM

    • Refrigerate after centrifugation.

  • Transport Temperature: Refrigerate

Rejection Criteria

  • Quantity not sufficient (QNS)

Specimen Stability

Ambient: 12 hours
Refrigerate: 7 days
Frozen: aliquot serum for longer storage
Laboratory Retention: 30 days

Test Frequency

Available Monday through Friday, usual TAT 1-3 days.

Reference Range

<0.35 kU/L

Performing Department

IMMUNOCHEMISTRY

Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI

Methodology

ImmunoCAP® System Fluorescence Enzyme Immunoassay (FEIA)

CPT

86003

CDM Code

80101978

Epic Test ID

1230102323

LOINC

26049-7

Beaker LOINC

CEDAR IGE: 26049-7

Mayo Access Code

Currently unavailable

Additional Information

Lab Staff:
For 1 allergen: 0.3mL serum
For more than 1 allergen: (0.05 mL x number of allergens) + 0.25mL dead space
1 tube per panel

Reviewed Date

12/13/2021

Beaker Names

Beaker Procedure Name: ALLERGEN CEDAR IGE
Beaker Display Name: Allergen Cedar IgE
BEAKER TEST NAME: Allergen Cedar IgE
BEAKER TEST REPORT NAME: Allergen Cedar IgE

Beaker Synonyms

No synonym on file

Beaker Location, Container and Temperature

BW IMMUNOCHEM: GOLD TOP SST TUBE ALLERGY (Preferred)-Refrigerated