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HelpEpic Code LAB1230879 CXCR4 Mutation Analysis
Test Name Alias
MYD88 | CXCR4
Interface Order Alias
1230879
Quick Collect
Clinical Information
Studies have shown that mutations in this gene are found in up to 40% of patients with Waldenstrom Macroglobulinemia/Lymphoplasmacytic Lymphoma (WM/LPL) and can impact ibrutinib response.
Ordering Instructions
Typically ordered by pathologists
Specimen Type
Bone Marrow or Blood
Collection Instructions
Submit only one specimen type*:
| Specimen Collection: Bone Marrow |
|---|
Container(s): Lavender top or Pink top (EDTA)
Preferred Volume to Collect: 3.0 mL
Minimum Volume to Collect: 1.0 mL
| Specimen Collection: Blood |
|---|
Container(s): Lavender top or Pink top (EDTA)
Preferred Volume to Collect: 3.0 mL
Minimum Volume to Collect: 1.0 mL
Neonate Volume to Collect: 1.0 mL (2 microtainers)
Capillary collect ok? Yes
Microtainer acceptable: Yes
Collection Instructions:
- Gently invert EDTA tube(s) 8 - 10 times after collection.
- Offsite/Phlebotomist instructions:
- Centrifuge/Spin: No
- Aliquot: Yes
- Transport Temperature: Ambient (room temperature)
| Specimen Type: Formalin-fixed, paraffin-embedded tissue (FFPE) Bone Marrow clot |
|---|
Collection Instructions: Area of interest marked on block or accompanying H&E slide.
Specimen Transport Temperature
Ambient (room temperature)
Specimen Stability
Whole Blood/Bone Marrow
Ambient: 72 hours
Refrigerate: 7 days
Frozen: Not Available
Laboratory Retention: Extracted DNA retained greater than 1 year
FFPE Bone Marrow Clot
Ambient: Forever
Laboratory Retention: Extracted DNA retained greater than 1 year
Test Frequency
Performed once per week
Usual turn-around time, less than 7 days
Reference Range
Not detected
Performing Department
Molecular Diagnostics
Performing Department Laboratory Location
Corewell Health Advanced Technology Laboratory (ATL), Grand Rapids, MI
Methodology
Next generation sequencing by Ion AmpliSeq technology
CPT
81479
CDM Code
3008147911
Epic Test ID
1230102546
Reviewed Date
Under Review (2/21/24)