Epic Code LAB2111147 Platelet Aggregation Studies
Test Name Alias
Platelet Aggregation Studies | Plt Aggregation Studies | 8429
Interface Order Alias
1230713
Clinical Information
Useful for evaluating platelet dysfunction due to congenital or acquired, qualitative platelet disorders. Test utilizes the Platelet Rich Plasma for the measurement of platelet aggregation using known platelet agonists.
Contraindications: Not indicated for patients taking medications that are known to inhibit platelet function. Medications which can inhibit platelet function include aspirin and anti-inflammatory drugs, anti-platelet drugs which include clopidogrel and imidazole. Yet, there are numerous other medications whose principal role is not to inhibit platelet function but nonetheless can do so e.g. antibiotics, anti-depressants, beta-blockers etc. Please contact the ordering physician before discontinuing any medications.
Platelet aggregation testing may require a coagulation consult with a pathologist prior to scheduling.
Testing recommendations:
Ordering Instructions
Must be scheduled in advance by a healthcare provider.
Icons & Photos
x8 Blue
Collection Instructions
Specimen Type: Whole Blood
Container/Tube: 8 x 2.7 mL blue top (3.2% Sodium Citrate) and 1 Lavender top (EDTA, 3 mL)
Collection Instructions:
Fasting specimen preferred, but not required.
Phlebotomy will draw syringes of venous blood from the patient using a 19-21 gauge needle.
- A clean venipuncture should be performed and blood should not be drawn from indwelling needles or catheters.
- Fill EIGHT 2.7 mL citrated (blue stoppered) tubes and ONE EDTA (lavender) tube for each patient being drawn.
- Remove the stoppers from the citrate and EDTA tubes.
- Remove the needle from the syringe.
- Gently dispense 2.7 mL whole blood from the syringe into each of the citrated tubes and whole blood into the EDTA tube.
- Replace stoppers tightly.
- Mix all tubes gently by inversion 5 - 10 times.
- Transport specimens to the lab immediately after collection.
- Do not send through the pneumatic tube system.
- Specimens must be hand delivered to the laboratory.
Detailed instructions (link): Anticoagulant Correction for High Hematocrit
Processing Instructions (Laboratory, Outpatient or Off-site collection)
Cannot be collected off-site.
Rejection Criteria
- Hemolysis
Specimen Stability
Ambient: 4 hours post-collection
Refrigerated: Not acceptable
Frozen: Not acceptable
Laboratory Retention: 24 hours
Test Frequency
Available Monday through Thursday, Downtown Campus only. Usual TAT 3 - 5 days.
Performed for scheduled patients Monday - Thursday from 7:30 a.m. to 9:30 a.m.
Reference Range
Normal Platelet Aggregation response to platelet agonists.
Abnormal Platelet Aggregation will be accompanied by a pathologist interpretation.
Performing Department
COAGULATION
Performing Department Laboratory Location
Spectrum Health Regional Laboratory (SHRL), Grand Rapids, MI
Methodology
Human platelet aggregation measured by absorbance using platelet rich plasma.
CPT
Arachidonic Acid, aggregation: CPT Code: 85576
ADP, aggregation: CPT Code: 85576
ADP, aggregation: CPT Code: 85576
Collagen, aggregation: CPT Code: 85576
Epinephrine, aggregation CPT Cod: 85576
Ristocetin, aggregation: CPT Code: 85576
Ristocetin, aggregation: CPT Code: 85576
Platelet Count: 85049
Hematocrit: 85014
Pathologist interpretation: CPT Code: 85576 -26
CDM Code
Not available
Epic Test ID
1230101044
LOINC
ADP 20 µM 33518-2
ADP 2.5 µM 33519-0
Ristocetin 1500 µg/mL 33522-4
Ristocetin 500 µg/mL 33523-2
Arachidonic Acid 500 µg/mL 24381-6
Collagen 10 µg/mL 24379-0
Epinephrine 300 µM 24378-2
Platelet: 777-3
Hct: 4544-3
Beaker LOINC
PLT ADP: 24377-4
PLT COLLAGEN: 24379-0
PLT EPINEPHRINE: 24378-2
PLT RISTOCETIN: 24380-8
PULL PLT CT AGGREGATION: N/A
Reviewed Date
10/11/2021
Beaker Names
Beaker Procedure Name: PLATELET AGGREGATION STUDIES
Beaker Display Name: Platelet Aggregation Studies
BEAKER TEST NAME: HEMATOCRIT PLATELET COUNT FOR AGGREGATION
BEAKER TEST REPORT NAME: HEMATOCRIT PLATELET FOR AGGR
Beaker Synonyms
No synonym on file
Beaker Collection and Specimen Handling
BEAKER COLLECTION: LOOK+LOOK
Beaker Location, Container and Temperature
BW COAGULATION: BLUE TOP TUBE (Preferred)-Ambient