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HelpEpic Code LAB2111421 Products of Conception Aneuploid Screen (XY, 13, 16, 18, 21) by FISH
Test Name Alias
POC Common Trisomies | FISH for Common Trisomies in POC | 995
Interface Order Alias
11435
Quick Collect
If ambient temperature exceeds 80°F or is below 40°F, please send in an insulated container.
Clinical Information
This probe panel detects abnormalities in the copy number of chromosomes 13, 16, 18, 21, X, and Y, which are commonly associated with pregnancy loss.
Ordering Instructions
Products of Conception Aneuploid Screen (XY, 13, 16, 18, 21) by FISH is a predictive and presymptomatic genetic test.
Submission of an order for any predictive genetic tests and presymptomatic genetic tests, as defined by MCL 333.17020, contained in this catalog constitutes certification to Corewell Health laboratories that the ordering physician understands that written, informed consent is required for these tests and that, by submitting an order for these genetic tests, ordering physician has obtained “Informed Consent” of subject patient as required by any applicable state or federal laws with respect to each test ordered. On occasion, we forward a specimen to an outside reference laboratory. Corewell Health laboratories may request that ordering physician provide such consent to Corewell Health upon a reasonable request.
For an example of an informed consent, click here.
Collection Instructions
Multiple specimen collection types. Submit only one:
Specimen Collection: Formalin-fixed, paraffin-embedded (FFPE) tissue
Container(s): Block
Preferred Volume to Collect: 6 unstained slides cut between 4 and 6 microns thick
Collection Instructions:
- Include an H&E slide scribed by Pathologist and Surgical Specimen Testing order sheet.
- Place specimen in 10% Formalin and order Tissue Pathology in addition to Products of Conception Aneuploid Screen (XY, 13, 16, 18, 21) by FISH order.
Specimen Collection: Products of Conception
Container(s): Sterile transport tube with tissue culture media
Preferred volume to collect: 1 cm3
Specimen Collection: Surgery/Autopsy biopsy
Container(s): Sterile transport tube with tissue culture media
Preferred volume to collect: 1 cm3
Processing Instructions (Laboratory, Outpatient or Off-site collection)
Spin: No
Aliquot: No
Transport Temperature: Ambient
If ambient temperature exceeds 80°F or is below 40°F, please send in an insulated container. All samples should be directed to the laboratory as soon as possible.
Specimen Stability
Ambient: 3 days for fresh specimens (beyond 3 days, specimen viability will be detemined by Cytogenetics Lab)
Laboratory Retention: primary specimens 4 weeks; frozen pellets retained greater than 1 year
Test Frequency
Test Set Up: Monday – Friday 8:00 am – 5:00 pm, Saturday 8:00 am – 3:00 pm.
Technologist on call for Sunday set up.
Final report: 2 – 5 days.
Reference Range
An interpretative report will be provided.
Performing Department
Cytogenetics
Performing Department Laboratory Location
Corewell Health Advanced Technology Laboratory (ATL), Grand Rapids, MI
Methodology
Performed by fluorscence in situ hybridization (FISH). This test was developed and its performance characteristics determined by Spectrum Health Cytogenetics Laboratory. It has not been cleared or approved by the US FDA. The FDA has determined that such clearance or approval is not necessary. This test is used for clinical purposes.
CPT
88271 x6, 88275 x3
CDM Code
3108827102, 3108827501
Epic Test ID
1230101054
Reviewed Date
4/28/2023