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Epic Code LAB311 Antithrombin III Activity

Important Note

There is currently a nationwide shortage of this tube. Please take steps to ensure specimen integrity to reduce recollection. Specimen Tube Shortage (link)

Test Name Alias

Antithrombin III Activity | AT III Activity | AT3 Activity | 8394

Interface Order Alias

10008

Clinical Information

ATIII is useful for the evaluation of ATIII deficiency congenital or acquired, resulting from low concentration and/or reduced functionality.

 

Direct thrombin inhibitors will cause erroneously increased Antithrombin III Activity. AT levels decrease during heparin therapy and may increase during coumadin therapy.

Icons & Photos

Collection Instructions

Specimen Collection: Blood

 

Container(s): 3.2% Na Citrate Tube (blue top)

Preferred Volume to Collect: 2.7 mL (full tube)

Minimum Volume to Collect: 1.8 mL (full tube)

Capillary collect ok: No

Microtainer acceptable: No

 

Collection Instructions:

 

Processing Instructions (Laboratory, Outpatient or Off-site collection)

  • Processed Specimen: Platelet Poor Plasma
  • Centrifuge/Spin: Yes
  • Aliquot: Yes
  • Processing Instructions:
    • Detailed Instructions (link): Preparing Platelet Poor Plasma
    • Separate into 2 aliquots, minimum of 0.5 mL each.
    • Freeze aliquots in plastic transport tubes immediately.
  • Transport Temperature:
    • Ambient (Up to 1 hour in whole blood state)
    • Frozen (Plasma Only >1 hour post collection)

Rejection Criteria

  • Hemolysis
  • Specimen has been thawed

Specimen Stability

Ambient: 1 hour in whole blood state

Refrigerate: not acceptable

Frozen: Plasma only > 1 hour post collection

Laboratory Retention: 2 months

Test Frequency

Testing available Monday - Friday, TAT 1-4 days

Reference Range

80 – 120 %

Performing Department

COAGULATION

Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI

Methodology

Chromogenic

CPT

85300

CDM Code

80101917

Epic Test ID

1230100356

LOINC

Antithrom 3 Act: 27811-9

Beaker LOINC

ANTITHROMBIN III ACTIVITY: 27811-9

Mayo Access Code

SHO8394

Reviewed Date

10/11/2021

Beaker Names

Beaker Procedure Name: ANTITHROMBIN III
Beaker Display Name: Antithrombin III Activity
BEAKER TEST NAME: ANTITHROMBIN III ACTIVITY
BEAKER TEST REPORT NAME: Antithrombin III Activity

Beaker Synonyms

No synonym on file

Beaker Collection and Specimen Handling

BEAKER COLLECTION: +(1)S10/POx3/F

Beaker Location, Container and Temperature

BW COAGULATION: BLUE TOP TUBE