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Epic Code LAB316 Low Molecular Weight (LMW) Heparin, Blood Level

Important Note

There is currently a nationwide shortage of this tube. Please take steps to ensure specimen integrity to reduce recollection. Specimen Tube Shortage (link)

Test Name Alias

Low Molecular Weight Heparin (Chromogenic substrate methodology) Blood Level |LMWH |Anti Xa Blood Level | Lovenox level | 8102

Interface Order Alias

10199

Clinical Information

Useful for the quantification of LMWH in patient plasma and verification of the intended target level.

 

Heparin considerably accelerates the inactivation of thrombin and coagulation factor Xa by antithrombin III.

 

Plasma low molecular weight heparin (LMWH) anti-Xa assay assayed using a low molecular weight heparin reference curve. This assay is valid only for low molecular weight heparin, and will not accurately reflect anti-Xa activity in patients on unfractionated heparin or danaparoid.

Icons & Photos

Collection Instructions

Specimen Collection: Blood

 

Container(s): 3.2% Na Citrate Tube (blue top)

Preferred Volume to Collect: 2.7 mL (full 2.7 mL blue tube)

Minimum Volume to Collect: 1.8 mL (full 1.8 mL blue white tube)

Capillary collect ok: No

Microtainer acceptable: No

 

Collection Instructions:

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Platelet Poor Plasma

Centrifuge/Spin: Yes

Aliquot: Yes

 

Processing Instructions:

  • Detailed instructions (link): Preparing Platelet Poor Plasma
  • Separate plasma into 1 – 2 aliquots, minimum of 0.5 mL each.
  • Freeze aliquots in plastic transport tubes immediately.

Transport Temperature:

  • Ambient (up to 1 hour in whole blood state)
  • Frozen (plasma only >1 hour)

Rejection Criteria

  • Hemolysis
  • Specimen has been thawed

Specimen Stability

Ambient: 1 Hour

Frozen: Aliquot and freeze platelet poor plasma within 1 hour of collection.

Laboratory Retention: 24 hours

Test Frequency

Available daily, usual TAT 4 hours

Reference Range

The therapeutic range for anticoagulation with LMW heparin has been reported to be 0.5-1.0 U/ml and the prophylactic range as 0.2-0.4 U/ml when measured by the anti-Xa method, with samples drawn 3-4 hours after SQ administration of either dalteparin or enoxaparin.  

 

Link: Laboratory Critical Values Table

Performing Department

COAGULATION

Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI

Methodology

Chromogenic Based Assay

CPT

85520

CDM Code

4094121

Epic Test ID

1230100896

Beaker LOINC

LMW HEPARIN (CHROMOGENIC SUBSTRATE METHODOLOGY): 3271-4

Mayo Access Code

SHO8102

Reviewed Date

10/11/2021

Beaker Names

Beaker Procedure Name: LOW MOLECULAR WGT HEPARIN
Beaker Display Name: Low Molecular Weight (LMW) Heparin, Blood Level
BEAKER TEST NAME: LMW HEPARIN
BEAKER TEST REPORT NAME: Low Molecular Weight Heparin

Beaker Synonyms

No synonym on file

Beaker Collection and Specimen Handling

BEAKER COLLECTION: LOOK+LOOK

Beaker Location, Container and Temperature

BW COAGULATION: BLUE TOP TUBE