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Epic Code LAB3340 Human Papilloma Virus (HPV) Type 16 and 18/45 mRNA test

Important Note

The APTIMA HPV Assay has only been validated for use with cervical specimens collected in PreservCyt Solution using a broom-type or cytobrush/spatula collection device.

Test Name Alias

HPV 16/18 45 | 251 | HPV 16/18 Genotype

Interface Order Alias

11653

Clinical Information

The APTIMA HPV 16 18/45 Genotype Assay can differentiate HPV 16 from HPV 18 and/ or HPV 45, but does not differentiate between HPV 18 and HPV 45. World-wide, HPV types 16, 18, and 45 are associated with approximately 80% of all invasive cervical cancers. These three types are found in 75% of all squamous carcinomas, with type 16 alone found in over 60% of all squamous carcinomas. In adenocarcinomas, HPV types 16, 18, and 45 are found in 80-94% of cases, with types 18 and 45 comprising almost half of these infections.

Specimen Requirements

Specimen Type: Cervical Specimen

Container/Tube: ThinPrep Pap Test vials containing PreservCyt Solution

Volume: 4.0 mL

Minimum volume: 2.0 mL

Specimen Transport Temperature

Ambient

Specimen Stability

Ambient: 30 days

Refrigerated: 105 days

Frozen: 24 months

Test Frequency

Test performed 2 - 3 times per week, usual TAT less than 7 days

Performing Department

CYTOLOGY

Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI

Methodology

APTIMA HPV 16 18/45 Genotype Assay

CPT

87625

CDM Code

3900391

Epic Test ID

1230100810

LOINC

HPV TYPE 16: 59263-4
HPV TYPE 18/45: 75694-0

Mayo Access Code

SHO251

Reviewed Date

7/2/2021