Epic Code LAB3619 TB Screen (QuantiFERON® Gold Plus)
Test Name Alias
TB | Tuberculosis | Mycobacterium tuberculosis (MTB) | QFT | IGRA | LTBI | MTB | 7105
Interface Order Alias
55059
Quick Collect
LOOK+LOOK
Clinical Information
A positive result should not be the sole or definitive basis for determining infection with M. tuberculosis. It should be followed by further medical evaluation for active tuberculosis disease (e.g., Acid fast bacilli (AFB) smear and culture, chest x-ray).
Diagnosing or excluding tuberculosis disease, and assessing the probability of Latent TB Infection (LTBI), requires a combination of epidemiological, historical, medical, and diagnostic findings that should be taken into account when interpreting QuantiFERON® Gold IT results. See General guidance on the diagnosis and treatment of TB disease and LTBI (http://cdc.gov/nchstp/tb/).
The performance of the USA format of the QFT test has not been extensively evaluated with specimens from individuals who have impaired or altered immune function, are younger than 17 years of age, or are pregnant.
Icons & Photos
Preferred Collection (1 tube) - 10 mL Lithium Heparin Green Non Gel tube |
Do not substitute 6.0 or 4.0 mL. Check that you are using Lithium and NOT Sodium. |
Collection Instructions
LINK: Collection Quick Guide
PREFERRED COLLECTION (1 TUBE) |
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Specimen Type: Blood
Collection Instructions:
Processing Instructions (Laboratory, Outpatient or Off-site collection)
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ALTERNATE COLLECTION (4 TUBE) |
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Spectrum Health is no longer supplying the 4-tube collection containers. If you need support on how to collect and process the 4-tube kit, please visit the vendor website using the Resources section on the left. Specimen will still be processed at the Laboratory.
It is recommended collection staff are trained on collection of TB Screen QuantiFERON® (QFT) 4 tube prior to collecting the specimen. Incorrect collection could lead to aberrant results. |
Lab Staff Instructions
- Transplant TB Screen (aka "Tspot") is only for patients with immunosuppressive conditions or those undergoing treatment with immunosuppressive drugs.
1 tube collection:
- Follows standard order of draw and collection
4 tube collection:
- Specimen must be incubated within 16 hours of collection at SHRL. PolicyTech: #24836
- Keep tubes at room temperature 22°C ± 5°C until placed in incubator for the gray, green, yellow and purple tubes. Policy Tech: #24836
- Multiple Labels should print for each TB Screen order, it does not matter which suffix letter goes on what tube.
Specimen Stability
Lithium tube (1 tube):
- Ambient: 15 minutes to 3 hours before refrigeration.
- Refrigerated: Up to 48 hours before transfer to single tubes and incubation.
(Once arrived in lab)
- Transfer to QFT tubes: Specimen must be brought to room temperature before transfer to QFT single tubes.
- Incubation: QFT Single tubes should be placed in 37° C within two hours of transfer. Total time from blood draw to incubation should not exceed 53 hours.
- Lithium tube NOT refrigerated: MUST be transferred to the QFT single tubes within 12 hours of collection.
QFT 4 Tube set:
- Ambient: 16 hours after collection
Laboratory Retention: 5 days
Test Frequency
Available Monday through Friday, usual turn-around time 2 to 4 days.
Reference Range
Negative
Performing Department
Immunochemistry
Performing Department Laboratory Location
Corewell Health Reference Laboratory, Grand Rapids, MI
Methodology
Interferon-gamma release assay
CPT
86480
Professional Fee for Pathologist Interpretation may apply
CDM Code
3028648001
Epic Test ID
1230101919
LOINC
QuantiFERON-TB Gold: 71775-1
Mayo Access Code
SHO55059
Additional Information
As of 9/18/2018, three-tube collection kits are no longer accepted and will be canceled.
Reviewed Date
12/13/2022