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Epic Code LAB3623 IgE Hazelnut Component Add-On

Test Name Alias

allergen | ImmunoCAP | Allergen Specific IgE | RAST | Allergy | Tree Nut | 7106

Interface Order Alias

55079

Clinical Information

IgE antibodies to rCor a 1 (Hazelnut PR-10 Protein) are primarily associated with localized reactions to hazelnut and a lower risk of systemic reactions.

 

IgE antibodies to rCor a 8 (Hazelnut LTP) may be associated with both local and systemic reactions, including anaphylaxis. This antigen may also cross react with antibodies to peach antigens.

 

IgE antibodies to rCor a 9 ((Hazelnut Storage Protein) are associated with a higher risk of systemic reactions, including anaphylaxis.

 

IgE antibodies to rCor a 14 (Hazelnut Storage Protein) are associated with a higher risk of systemic reactions, including anaphylaxis.

 

Component testing for Hazel Nut must be ordered as follow-up to whole allergen results.They are not available as reflex tests. Patient specimens are stored frozen for 30 days.

 

Component testing measures IgE antibodies to individual proteins unlike whole allergen testing which measures the presence of specific immunoglobulin E (sIgE) antibodies to a combination of allergenic and non-allergenic proteins. This next generation testing identifies the source of sensitization and helps the clinician assess the risk of systemic reaction.

 

Results of component testing can assist with patient selection for oral food challenge as well as possible management recommendations such as immunotherapy and/or allergen avoidance/food elimination. Because of the diagnostic and management complexities associated with food allergy, referral to an allergy and immunology specialist should be considered when evaluating a patient with suspected food allergies.

Specimen Requirements

Specimen Collection: Blood

Container(s): Gold Top (Serum Separator-SST Gel)

Preferred Volume to Collect: 3.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok? Y

Microtainer acceptable? Y

 

Processed specimen: Serum

Centrifuge/Spin: Y

Aliquot: N

Processing instructions: Allow specimen to clot for 30 minutes and centrifuge within 2 hours.

Specimen Transport Temperature

Refrigerate

Rejection Criteria

Quantity not sufficient (QNS)

Specimen Stability

Serum

Ambient: 12 hours

Refrigerate: 7 days

Frozen: aliquot for longer storage

Laboratory Retention: 30 days

Test Frequency

Available Monday through Friday, usual TAT 1-3 days.

Reference Range

<0.10 kU/L

Performing Department

IMMUNOCHEMISTRY

Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI

Methodology

ImmunoCAP® System Fluorescence Enzyme Immunoassay (FEIA)

CPT

86008

CDM Code

4026787

Epic Test ID

1230101923

Beaker LOINC

HAZELNUT NCOR A 9 IGE: N/A
HAZELNUT RCOR A 1, PR-10 IGE: N/A
HAZELNUT RCOR A 14 IGE: N/A
HAZELNUT RCOR A 8, LTP IGE: N/A

Mayo Access Code

SHO55079

Reviewed Date

12/13/2021

Beaker Names

Beaker Procedure Name: HAZELNUT COMPONENTS IGE PANEL
Beaker Display Name: Hazelnut Components IgE Panel
BEAKER TEST NAME: ALLERGEN HAZELNUT COMPONENTS IGE PANEL
BEAKER TEST REPORT NAME: Allergen Hazelnut Components IGE Panel

Beaker Synonyms

HAZELNUT COMPONENTS IGE PANEL

Beaker Location, Container and Temperature

BW IMMUNOCHEM: GOLD TOP SST TUBE ALLERGY (Preferred)-Refrigerated