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Test Code LAB3653 Cardiolipin IgG and IgM Antibodies

Test Name Alias

Anti-phospholipid Antibody | Anti-cardiolipin Screen | Cardiolipin Screen | 7159

Clinical Information

Cardiolipin IgG/IgM and Beta Glycoprotein 1 IgG/IgM Antibodies when used in conjunction with other clinical findings, aid in the diagnosis of primary Antiphospholipid Syndrome (APS) and those secondary to systemic lupus erythematosus (SLE) or SLE-like disorders. Antibody profiles are encouraged to identify thrombotic risk and may be more useful than individual tests in identifying a patient's risk.

Panel Information

This test is part of Panel: Antiphospholipid Antibody Syndrome Panel [LAB1230572] 

Collection Instructions

Specimen Collection: Blood

Container(s): Gold Top (Serum Separator-SST Gel)

Preferred Volume to Collect: 5.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok: Yes

Microtainer acceptable: Yes

Collection Instructions:

  • After collection, gently invert tube 8-10 times.
  • Specimen should be processed within 2 hours – See Processing Instructions.

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Serum

Centrifuge/Spin: Yes

Aliquot: No

Processing Instructions:

  • Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.

Transport Temperature: Refrigerate

Rejection Criteria

Specimen not centrifuged within 2 hours

Specimen Stability

Ambient: 12 Hours

Refrigerate: 7 days (2-8° C)

Frozen: -20°C for longer storage

Laboratory Retention: 7 days

Test Frequency

Test available Monday - Friday. Turn-around time 1 - 3 days.

Reference Range

both IgG and IgM:

<20 U/mL Negative

≥ 20 U/mL Positive

Performing Department


Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI


Multiplex Flow Immunoassay


86147 | 86147

CDM Code

4088535 IGG | 4088536 IGM


Epic Test ID


Interface Order Alias


Interface Information

Cerner Order Code: 55115

Cerner Result Code: 20073 IgG | 20072 IgM

Mayo Access Code

Not available

Additional Information

This test replaces Cardiolipin Antibody Screen and Cardiolipin Screen, IgG, IgM if positive

Reviewed Date