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Test Code LAB501 Toxoplasma IgG Antibody (do not use)

Important Note

This test is currently not available to order.

Please refer to this test for ordering and collection instructions: Toxoplasma Antibody, IgG

Test Name Alias

Toxoplasmosis | Toxoplasma gondii IgG | Torch | ToRC

Clinical Information

Intended for the qualitative detection of IgG anitobodies Toxoplasma gondii. 

Collection Instructions

Specimen Collection: Blood

Container(s): Gold Top (Serum Separator-SST Gel)

Preferred Volume to Collect: 5.0 mL

Minimum Volume to Collect: 1.0 mL

Neonate Volume to Collect: 1.0 mL

Capillary collect ok: Yes

Microtainer acceptable: Yes

Collection Instructions:

  • Gently invert gold tube(s) 8 - 10 times to mix clot activator with blood.
  • Specimen should be processed within 2 hours – See Processing Instructions.

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Serum

Centrifuge/Spin: Yes

Aliquot: No

Minimum Serum Volume: 1.0 mL

Processing Instructions:

  • Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.

Transport Temperature: Refrigerate

Rejection Criteria

Specimen not centrifuged within 2 hours

Specimen Stability

Ambient: 3 days

Refrigerate: 7 days

Frozen: aliquot serum for longer storage at-20C or colder

Laboratory Retention: 7 days

Test Frequency

Available Monday through Friday, usual TAT 1-3 days.

Reference Range

Negative

Results Interpretation

Results Interpretation
Negative Patient is presumed not to have had a previous T. gondii infection
Equivocal Equivocal results: obtain an additional sample for re-testing
Positive IgG Antibody to T.gondii detected which may indicated current or pat T.gondii infection

 Toxoplasmosis IgG & IgM Interpretation

 

T. gondii IgG

Result

 

T. gondii IgM

Result

 

Result Interpretation

Negative

Negative

No serologic evidence of infection with T. gondii

Negative

Equivocal

Possible early acute infection or false-positive IgM reaction. Obtain a new specimen for IgG and IgM testing. If the new specimen result remains the same, the patient is probably a false-positive.

Negative

Positive

Possible acute infection or false-positive IgM result. Obtain a new specimen for IgG and IgM testing. If results from the second specimen remain the same, the IgM reaction is probably a false-positive.

Equivocal

Negative

Equivocal: obtain a new specimen for both IgG and IgM testing.

Equivocal

Equivocal

Equivocal: obtain a new specimen for both IgG and IgM testing.

Equivocal

Positive

Possible acute infection with T.gondii. Obtain a new specimen for IgG and IgM testing. If results with the new specimen remain the same or the IgG becomes positive, both specimens should be sent to a reference laboratory with experience in the diagnosis of toxoplasmosis.

Positive

Negative

Infected with T. gondii for more than one year.

Positive

Equivocal

Infected with T. gondii for probably more than one year or false-positive IgM reaction. Obtain a new specimen for IgG and IgM testing. If results from the second specimen remain the same, both specimens should be sent to a reference laboratory with experience in the diagnosis of toxoplasmosis.

Positive

Positive

Possible recent infection within the last 12 months. Send the specimen to a reference laboratory with experience in the diagnosis of toxoplasmosis.

*Adapted from FDA Publication: “Limitations of Toxoplasma IgM commercial Test Kits” July  25,1997

 

Performing Department

IMMUNOCHEMISTRY

Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI

Methodology

Multiplex Flow Immunoassay

CPT

86777

CDM Code

4088561

Epic Test ID

Unavailable

Interface Order Alias

Unavailable

Mayo Access Code

Unavailable

LOINC

5388-4

Reviewed Date

Under Review