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Test Code LAB659 Toxoplasma IgM Antibody (do not use)

Important Note

This test is currently not available to order.

Please refer to this test for ordering and collection instructions: Toxoplasma IgM Antibody

Test Name Alias

Torch | ToRC | Toxoplasma gondii IgM | Toxoplasmosis

Clinical Information

Intended as an aid in the diagnosis of current or recent Toxoplasma gondii infection, including women of child-bearing age.

Per the FDA, IgM positive results by a screening assay should be confirmed, for example with Toxoplasma PCR method.

Collection Instructions

Specimen Collection: Blood

Container(s): Gold Top (Serum Separator-SST Gel)

Preferred Volume to Collect: 5.0 mL

Minimum Volume to Collect: 1.0 mL

Neonate Volume to Collect: 1.0 mL

Capillary collect ok: Yes

Microtainer acceptable: Yes

Collection Instructions:

  • Gently invert gold tube(s) 8 - 10 times to mix clot activator with blood.
  • Specimen should be processed within 2 hours – See Processing Instructions.

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Serum

Centrifuge/Spin: Yes

Aliquot: No

Minimum Serum Volume: 1.0 mL

Processing Instructions:

  • Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.

Transport Temperature: Refrigerate

Rejection Criteria

Specimen not centrifuged within 2 hours

Specimen Stability

Ambient: 3 days

Refrigerate: 7 days

Frozen: aliquot serum for longer storage at -20C or colder

Laboratory Retention: 7 days

Test Frequency

Available Monday through Friday, usual TAT 1-3 days.

Reference Range

Negative

Results Interpretation

Results Interpretation
Negative Toxo IgM antibody was not detected
Equivocal Equivocal results: Toxo IgM status not determined. Obtain an additional sample within an appropriate timeframe (collected in 2-3 weeks) for re-testing
Positive Toxo IgM antibody detected which may indicate a current or recent infection

 

Toxoplasmosis IgG & IgM Interpretation

T. gondii IgG

Result

T. gondii IgM

Result

Result Interpretation

Negative

Negative

No serologic evidence of infection with T. gondii

Negative

Equivocal

Possible early acute infection or false-positive IgM reaction. Obtain a new specimen for IgG and IgM testing. If the new specimen result remains the same, the patient is probably a false-positive.

Negative

Positive

Possible acute infection or false-positive IgM result. Obtain a new specimen for IgG and IgM testing. If results from the second specimen remain the same, the IgM reaction is probably a false-positive.

Equivocal

Negative

Equivocal: obtain a new specimen for both IgG and IgM testing.

Equivocal

Equivocal

Equivocal: obtain a new specimen for both IgG and IgM testing.

Equivocal

Positive

Possible acute infection with T.gondii. Obtain a new specimen for IgG and IgM testing. If results with the new specimen remain the same or the IgG becomes positive, both specimens should be sent to a reference laboratory with experience in the diagnosis of toxoplasmosis.

Positive

Negative

Infected with T. gondii for more than one year.

Positive

Equivocal

Infected with T. gondii for probably more than one year or false-positive IgM reaction. Obtain a new specimen for IgG and IgM testing. If results from the second specimen remain the same, both specimens should be sent to a reference laboratory with experience in the diagnosis of toxoplasmosis.

Positive

Positive

Possible recent infection within the last 12 months. Send the specimen to a reference laboratory with experience in the diagnosis of toxoplasmosis.

Performing Department

IMMUNOCHEMISTRY

Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI

Methodology

Multiplex Flow Immunoassay

CPT

86778

CDM Code

4088560

Epic Test ID

Unavailable

Interface Order Alias

Unavailable

Mayo Access Code

Unavailable

LOINC

Toxoplas Ab IgM: 40678-5

Reviewed Date

Under Review