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Epic Code LAB7610 FDP (Fibrin Degradation Products)

Important Note

There is currently a nationwide shortage of this tube. Please take steps to ensure specimen integrity to reduce recollection. Specimen Tube Shortage (link)

Test Name Alias

Fibrin Degradation Products | 8415 | Fibrin Split Products

Interface Order Alias


Clinical Information

Useful for the detection and semi-quantitation of fibrin/fibrinogen degradation products in plasma with latex particles which are coated with monoclonal antibodies to FDP. 


Abnormal fibrinolytic and or fibrinogenolytic activity demonstrated by elevated levels of FDP in plasma may be seen in the following:

  • DIC
  • Eclampsia
  • Carcinoma
  • Post-operative
  • Cardiac or hepatic disorders
  • Fibrinolysis
  • Pulmonary embolism
  • Deep vein thrombosis



Free D and E domains as well as X and Y fragments detected by this method may be produced by degradation of either fibrin clot or circulating fibrinogen.

In cases where the FDP assay is positive and it is desired to distinguish lysis of fibrin from intravascular fibrinolysis, it is recommended to suggest the D-Dimer assay.



The slightest coagulation of the specimen may produce false positive reactive with the FDP plasma.  High levels of rheumatoid factor (RF) may lead to false agglutinations.  Any suspected presence of RF should be confirmed by a separate test for RF. 

The FDP Plasma test is insensitive to heparins up to 2 IU/ml.

The presence of anti-mouse of antibodies in certain subjects may lead to aberrant test results.

Collection Instructions

Specimen Collection: Blood


Container(s): 3.2% Na Citrate Tube (blue top)

Preferred Volume to Collect: 2.7 mL (full tube)

Minimum Volume to Collect: 1.8 mL (full tube)

Capillary collect ok: No

Microtainer acceptable: No


Collection Instructions:

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Platelet Poor Plasma


Centrifuge/Spin: Yes

Aliquot: Yes


Processing Instructions:

  • Detailed instructions (link): Preparing Platelet Poor Plasma
  • Separate plasma into 1 – 2 aliquots, minimum of 0.5 mL each.
  • Freeze aliquots in plastic transport tubes immediately.

Transport Temperature:

  • Ambient (up to 1 hour in whole blood state)
  • Frozen (plasma only >1 hour)

Rejection Criteria

  • Hemolysis
  • Specimen has been thawed

Specimen Stability

Ambient: 4 hours following centrifugation (8 hours if spun and plasma aliquoted, <1 hour if unspun)

Frozen: Aliquot plasma for longer storage

Laboratory Retention: 24 hours

Test Frequency

Available 24 hours, TAT 1 day.

Reference Range

<5 µg/mL

Performing Department


Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI
Corewell Health Blodgett Laboratory, Grand Rapids, MI


Rapid latex slide agglutination test using mouse anti-FDP antibodies



CDM Code


Epic Test ID



FDP: 29263-1

Mayo Access Code


Reviewed Date