Epic Code LAB7610 Fibrin Degradation Products (FDP)
Test Name Alias
Fibrin Degradation Products | FDP | 8415
Interface Order Alias
10039
Clinical Information
Useful for the detection and semi-quantitation of fibrin/fibrinogen degradation products in plasma with latex particles which are coated with monoclonal antibodies to FDP.
Abnormal fibrinolytic and or fibrinogenolytic activity demonstrated by elevated levels of FDP in plasma may be seen in the following:
- DIC
- Eclampsia
- Carcinoma
- Post-operative
- Cardiac or hepatic disorders
- Fibrinolysis
- Pulmonary embolism
- Deep vein thrombosis
Interpretation:
Free D and E domains as well as X and Y fragments detected by this method may be produced by degradation of either fibrin clot or circulating fibrinogen.
In cases where the FDP assay is positive and it is desired to distinguish lysis of fibrin from intravascular fibrinolysis, it is recommended to suggest the D-Dimer assay.
Limitations:
The slightest coagulation of the specimen may produce false positive reactive with the FDP plasma. High levels of rheumatoid factor (RF) may lead to false agglutinations. Any suspected presence of RF should be confirmed by a separate test for RF.
The FDP Plasma test is insensitive to heparins up to 2 IU/ml.
The presence of anti-mouse of antibodies in certain subjects may lead to aberrant test results.
Icons & Photos
Collection Instructions
Specimen Collection: Blood
Container(s): 3.2% Na Citrate Tube (blue top)
Preferred Volume to Collect: 2.7 mL (full tube)
Minimum Volume to Collect: 1.8 mL (full tube)
Capillary collect ok: No
Microtainer acceptable: No
Collection Instructions:
-
Detailed instructions (link): Anticoagulant Correction for High Hematocrit
-
Detailed instructions (link): Blue Citrate Tube
- Specimen should be processed within 1 hour – See Processing Instructions below.
Processing Instructions (Laboratory, Outpatient or Off-site collection)
Processed Specimen: Platelet Poor Plasma
Centrifuge/Spin: Yes
Aliquot: Yes
Processing Instructions:
- Detailed instructions (link): Preparing Platelet Poor Plasma
- Separate plasma into 1 – 2 aliquots, minimum of 0.5 mL each.
- Freeze aliquots in plastic transport tubes immediately.
Transport Temperature:
- Ambient (up to 1 hour in whole blood state)
- Frozen (plasma only >1 hour)
Rejection Criteria
- Hemolysis
- Specimen has been thawed
Specimen Stability
Ambient: 1 hour (8 hours if spun and plasma aliquoted
Frozen: Aliquot plasma for longer storage
Laboratory Retention: 24 hours
Test Frequency
Available 24 hours, TAT 1 day.
Reference Range
<5 µg/mL
Performing Department
COAGULATION
Performing Department Laboratory Location
Spectrum Health Regional Laboratory, Grand Rapids, MI
Spectrum Health Blodgett Laboratory, Grand Rapids, MI
Methodology
Rapid latex slide agglutination test using mouse anti-FDP antibodies
CPT
85362
CDM Code
4098415
Epic Test ID
1230100688
LOINC
FDP: 29263-1
Beaker LOINC
FIBRIN DEGREDATION PRODUCTS: 29263-1
Mayo Access Code
SHO10039
Reviewed Date
10/11/2021
Beaker Names
Beaker Procedure Name: FIBRIN SPLIT PRODUCTS
Beaker Display Name: Fibrin Degradation Products (FDP)
BEAKER TEST NAME: FDP
BEAKER TEST REPORT NAME: FDP
Beaker Synonyms
FIBRIN DEGRADATION PRODUCTS
Beaker Location, Container and Temperature
BW COAGULATION: BLUE TOP TUBE
BL COAGULATION: BLUE TOP TUBE