Sign in →

Epic Code LAB822 Methadone Level

Test Name Alias

Dolophine | 4088

Interface Order Alias

10430

Collection Instructions

Specimen Collection: Blood

 

Container(s): Gray Top (Potassium Oxalate and Sodium Fluoride) or Red top (no additive)

Preferred Volume to Collect: 6.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok? Yes

Microtainer acceptable?  Yes

 

Collection Instructions:

  • After collection, gently invert tube 8-10 times.
  • Gray Top is preferred tube.
  • Specimen should be processed – See Processing Instructions.

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Plasma or Serum

Centrifuge/Spin: Yes

Aliquot: Yes

 

Processing Instructions:

  • Gray top:
    • Centrifuge after collection
    • Pipette plasma into aliquot tubes
  • Red top:
    • When tubes are clotted (30-45 minutes), centrifuge specimens
    • Pipette serum into aliquot tube

Minimum plasma/serum volume: 1.0 mL

 

Transport Temperature: Ambient

Specimen Stability

Ambient: 72 hours

Refrigerate: 7 days

Frozen: 14 days

Laboratory Retention: 7 days

Test Frequency

Available 24 hours, usual TAT 1-3 days.

STAT TAT 4 hours.

Reference Range

The therapeutic range for methadone is 30-80 ng/mL, single dose.

(200 – 1100 ng/mL maintenance patient).

EDDP – only detectable in chronic use.

Performing Department

TOXICOLOGY

Performing Department Laboratory Location

Spectrum Health Regional Laboratory, Grand Rapids, MI

Methodology

Liquid Chromatography-Mass Spectrometry

 

This test was developed and its performance characteristics determined by Spectrum Health Toxicology Laboratory. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.

 

CPT

80358-LAB-METHADONE LEVEL
HCPCS: G0480

CDM Code

4024088

Epic Test ID

1230100926

LOINC

Methadone Lvl: 3772-1

Methadone met (EDDP): 17259-3

Beaker LOINC

METHADONE LEVEL: 3772-1
METHADONE METABOLITE (EDDP) LEVEL: 17259-3

Mayo Access Code

SHO4088

Additional Information

Gold Top SST not acceptable

Reviewed Date

12/6/2021

Beaker Names

Beaker Procedure Name: METHADONE LVL
Beaker Display Name: Methadone Level
BEAKER TEST NAME: METHADONE
BEAKER TEST REPORT NAME: Methadone

Beaker Synonyms

No synonym on file

Beaker Collection and Specimen Handling

BEAKER COLLECTION: +S/PO/A

Beaker Location, Container and Temperature

BW TOXICOLOGY: 6 ML GRAY TOP TUBE A (Preferred)-Ambient
BW TOXICOLOGY: RED TOP TUBE R (Acceptable)-Ambient