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Epic Code LAB8340 Prothrombin G20210A

Important Note

Similar Test Names:

  • This test is also known as Factor II Mutation. For Factor II Activity please order test #LAB303.
  • For Prothrombin Time (Protime with INR, PTINR) please order test #LAB320

 

Please review Ordering Instructions

Test Name Alias

Prothrombin G20210A | Factor II G20210A | PT G20210A | Factor II Mutation | Prothrombin Mutation | Prothrombin G20210 | Prothrombin Mutation Analysis | 78 | PT2

Interface Order Alias

10510

Quick Collect

+A

Clinical Information

Detects point mutation G20210A in the prothrombin gene, and is suggested for patients with inherited thrombophilia.

Patients on heparin therapy and blood transfusion patients may have blood specimens that potentially interfere leading to invalid or erroneous results

Ordering Instructions

Prothrombin G20210A is a predictive and presymptomatic genetic test.

 

Submission of an order for any predictive genetic tests and presymptomatic genetic tests, as defined by MCL 333.17020, contained in this catalog constitutes certification to Corewell Health laboratories that the ordering physician understands that written, informed consent is required for these tests and that, by submitting an order for these genetic tests, ordering physician has obtained “Informed Consent” of subject patient as required by any applicable state or federal laws with respect to each test ordered. On occasion, we forward a specimen to an outside reference laboratory. Corewell Health laboratories may request that ordering physician provide such consent to Corewell Health upon a reasonable request.

 

For an example of an informed consent, click here.

 

Collection Instructions

Specimen Collection: Blood

 

Container(s): Lavender Top (EDTA) 3.0 mL

Preferred Volume to Collect: 3.0 mL

Minimum Volume to Collect: 1.0 mL

Neonate Volume to Collect: 1.0 mL

 

Collection Instructions:

  • Gently invert 8 - 10 times after collection.
  • For optimal results, specimen should be received within 24 hours of collection. Send specimen same day of collection.

  • If one or more of the following tests are ordered simultaneously, only one EDTA tube needs to be collected:

    • Factor V Leiden DNA Analysis
    • Prothrombin G20210A

 

Processing Instructions (Laboratory, Outpatient or Off-site collection)

  • Processed Specimen: Whole Blood EDTA
  • Centrifuge/Spin: No
  • Aliquot: No
  • Transport Temperature: Ambient

Specimen Stability

Ambient: 24 hours

Refrigerated: 15 days

Laboratory Retention: 3 months

Test Frequency

Available at least twice per week, usual TAT 3 – 5 days.

Reference Range

Negative

Performing Department

Molecular Diagnostics

Performing Department Laboratory Location

Corewell Health Advanced Technology Laboratory (ATL), Grand Rapids, MI

Methodology

Multiplex Polymerase Chain Reaction (PCR) followed by detection using scorpion probes

CPT

81240

CDM Code

3108124001

Epic Test ID

1230101098

LOINC

Prothrombin G20210A: 24475-6

Prothrombin G20210A Interp: 8251-1

Mayo Access Code

SHO078

Reviewed Date

6/22/2023