Epic Code LAB848 Somatostatin (Somatotropin Release-Inhibiting Factor, SRIF)
Additional Codes
Mayo Code: FSOMA
Performing Laboratory
Inter Science InstituteSpecimen Type
GI PlasmaSpecimen Required
Patient preparation:
 1. Patient should be fasting 10-12 hours prior to collection.
 2. Patient should not be on any medications that affect insulin secretion or intestinal motility, if possible for at least 48 hours prior to collection.
Specimen Type: GI Plasma
Container/Tube: EDTA tube containing GI preservative: EDTAGI
Specimen Volume: 3 mL
Collection Instructions: Collect 10 mL of blood in special tube containing G.I. Preservative (T125). Specimen should be separated immediately and send 3 mL plasma frozen as soon as possible.
COLLECTION NOTE: Volumes listed are in serum or plasma, draw approximately 2 1/2 times the requested volume in whole blood.
Specimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
GI Plasma | Frozen | 180 days |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | Reject |
Other | Specimens other than Plasma collected in GI preservative (T125). |
Day(s) Performed
Monday through Friday
Reference Values
Up to 25 pg/mL
Clinical Information
Somatostatin is a cyclic peptide originally isolated from sheep hypothalami and shown to inhibit the release of Growth Hormone. Somatostatin is present primarily in three main forms: a 14 amino acid peptide, a 28 amino acid peptide (“Big†Somatostatin), and a 12,000 molecular weight ProSomatostatin. This assay measures only the 14 amino acid form of Somatostatin. All three forms of Somatostatin have similar biological properties and overall potencies. Somatostatin is a physiological regulator of islet cell and gastrointestinal functions and is a suppressor of many pituitary hormones including Growth Hormone, Prolactin, and Thyrotropin (TSH). Somatostatin levels are often elevated in diabetics, but the levels return to normal upon correction of the hormonal and metabolic deficiencies present. In many cases of APUDomas including VIPoma, Insulinoma, Glucagonoma, and Gastrinoma, elevated levels of Somatostatin are found. Â
Reporting Name
Somatostatin (Plasma)Method Name
Direct Radioimmunoassay (RIA)
CPT Code Information
84307
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
FSOMA | Somatostatin (Plasma) | 2961-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
Z0933 | Somatostatin, (Plasma) | 2961-1 |